Enzyme logic gate associated with a single responsive microparticle: scaling biocomputing to microsize systems

Valeriya Bychkova; Alexey Shvarev; Jian Zhou; Marcos Pita; Evgeny Katz

doi:10.1039/B917611J

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Chemical Communications

Issue 1, 2010

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Enzyme logic gate associated with a single responsive microparticle: scaling biocomputing to microsize systems

Valeriya Bychkova , Alexey Shvarev , Jian Zhou , Marcos Pita and Evgeny Katz

Chem. Commun., 2010, 46, 94-96

DOI: 10.1039/B917611J
Received 26 Aug 2009, Accepted 13 Oct 2009
First published on the web 03 Nov 2009

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Abstract
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A microsize biocomputing system based on enzyme logic processing biochemical signals was developed. Optical transduction of pH signals generated in situ by the enzyme OR logic gate was achieved with the use of a single optode microparticle.

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Preparation of optode microparticles and single-particlemeasurements of the signals generated by the enzyme logicgate
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Valeriya Bychkova
Alexey Shvarev
Jian Zhou
Marcos Pita
Evgeny Katz

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Chemical Communications

Enzyme logic gate associated with a single responsive microparticle: scaling biocomputing to microsize systems

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