Advances in chemical ligation strategies for the synthesis of glycopeptides and glycoproteins

Richard J. Payne; Chi-Huey Wong

doi:10.1039/B913845E

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Chemical Communications

Issue 1, 2010

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Advances in chemical ligation strategies for the synthesis of glycopeptides and glycoproteins

Richard J. Payne and Chi-Huey Wong

Chem. Commun., 2010, 46, 21-43

DOI: 10.1039/B913845E
Received 14 Jul 2009, Accepted 08 Sep 2009
First published on the web 30 Oct 2009

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A number of recent advances in the chemical synthesis of glycopeptides and glycoproteins are described, with particular focus on the development of peptide ligation strategies and their implementation in the convergent assembly of complex glycopeptides. Recent applications in the synthesis of full length homogeneous glycoproteins are also highlighted.

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Chemical Communications

Advances in chemical ligation strategies for the synthesis of glycopeptides and glycoproteins

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