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Issue 34, 2010
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Total synthesis of (±)-Vertine with Z-selective RCM as a key step

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Abstract

A concise total synthesis of the strained pentacyclic alkaloid (±)-Vertine has been achieved in eleven steps with the key steps being pelletierine condensation, Suzuki–Miyaura coupling, and ring-closing metathesis.

Graphical abstract: Total synthesis of (±)-Vertine with Z-selective RCM as a key step

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Publication details

The article was received on 14 Jun 2010, accepted on 09 Jul 2010, published on 11 Aug 2010 and first published online on 11 Aug 2010


Article type: Communication
DOI: 10.1039/C0CC01885F
Citation: Chem. Commun., 2010,46, 6264-6266
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    Total synthesis of (±)-Vertine with Z-selective RCM as a key step

    L. Chausset-Boissarie, R. Àrvai, G. R. Cumming, C. Besnard and E. P. Kündig, Chem. Commun., 2010, 46, 6264
    DOI: 10.1039/C0CC01885F

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