A “switching on” fluorescent chemodosimeter of selectivity to Zn2+ and its application to MCF-7 cells

Zhanxian Li; Mingming Yu; Lifeng Zhang; Ming Yu; Jinxia Liu; Liuhe Wei; Hongyan Zhang

doi:10.1039/C0CC01687J

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A “switching on” fluorescent chemodosimeter of selectivity to Zn²⁺ and its application to MCF-7cells†

Zhanxian Li,^a Mingming Yu,*^a Lifeng Zhang,^a Ming Yu,^a Jinxia Liu,^a Liuhe Wei*^a and Hongyan Zhang*^b

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* Corresponding authors

^a Department of Chemistry, Zhengzhou University, Zhengzhou, China
E-mail: yumm@zzu.edu.cn, weiliuhe@zzu.edu.cn
Fax: (+)86-371-67781205
Tel: (+)86-371-67781205

^b Key Laboratory of Photochemical Conversion and Optoelectronic Materials Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, China
E-mail: zhanghongyan@mail.ipc.ac.cn

Abstract

A highly sensitive and selective 1,8-naphthyridine-based fluorescent chemodosimeter for Zn²⁺ has been designed, synthesized, and applied to the detection of intracellular Zn²⁺.

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Article information

DOI: https://doi.org/10.1039/C0CC01687J
Article type: Communication
Submitted: 01 Jun 2010
Accepted: 13 Aug 2010
First published: 01 Sep 2010

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Chem. Commun., 2010,46, 7169-7171

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A “switching on” fluorescent chemodosimeter of selectivity to Zn²⁺ and its application to MCF-7 cells

Z. Li, M. Yu, L. Zhang, M. Yu, J. Liu, L. Wei and H. Zhang, Chem. Commun., 2010, 46, 7169 DOI: 10.1039/C0CC01687J

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