A highly selective and sensitive fluorescent probe for Hg2+ imaging in live cells based on a rhodamine–thioamide–alkyne scaffold

Weiying Lin; Xiaowei Cao; Yundi Ding; Lin Yuan; Lingliang Long

doi:10.1039/B927373E

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A highly selective and sensitive fluorescent probe for Hg²⁺ imaging in live cells based on a rhodamine–thioamide–alkyne scaffold†

Weiying Lin,*^a Xiaowei Cao,^a Yundi Ding,^a Lin Yuan^a and Lingliang Long^a

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* Corresponding authors

^a State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, Hunan 410082, P. R. China
E-mail: weiyinglin@hnu.cn
Fax: +86-731-88821464

Abstract

A new fluorescence turn-on probe for Hg²⁺ imaging in living cells was judiciously designed based on the interactions of Hg²⁺ to both thiol and alkyne moieties in a rhodamine scaffold, and the likely novel sensing mechanism has been proposed.

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Supplementary files

Experimental procedures, characterization data and additional spectra PDF (1380K)

Article information

DOI: https://doi.org/10.1039/B927373E
Article type: Communication
Submitted: 05 Jan 2010
Accepted: 16 Mar 2010
First published: 08 Apr 2010

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Chem. Commun., 2010,46, 3529-3531

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A highly selective and sensitive fluorescent probe for Hg²⁺ imaging in live cells based on a rhodamine–thioamide–alkyne scaffold

W. Lin, X. Cao, Y. Ding, L. Yuan and L. Long, Chem. Commun., 2010, 46, 3529 DOI: 10.1039/B927373E

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