Jump to main content
Jump to site search
Publishing
Advanced

Issue 3, 2010
Previous Article Next Article

Directed evolution of gold nanoparticle delivery to cells

Na Li,a  Timothy Larson,b  Hong H. Nguyen,a  Konstantin V. Sokolovb  and  Andrew D. Ellington*a 
Author affiliations

* Corresponding authors

a Department of Chemistry and Biochemistry, Institute for Cell and Molecular Biology, University of Texas at Austin, Austin, USA
E-mail: andy.ellington@mail.utexas.edu
Fax: +1 512 471 7014
Tel: +1 512 232 3424

b Department of Biomedical Engineering, University of Texas at Austin, Austin, USA

Abstract

A newly selected anti-receptor (anti-EGFR) aptamer was conjugated to gold nanoparticles via a facile hybridization method and was found to specifically and quantitatively direct the delivery of gold nanoparticles to cells expressing EGFR through receptor-mediated endocytosis.

Graphical abstract: Directed evolution of gold nanoparticle delivery to cells

Back to tab navigation
Download options Please wait...

Supplementary files

Publication details

The article was received on 06 Oct 2009, accepted on 10 Nov 2009 and first published on 24 Nov 2009


Article type: Communication
DOI: 10.1039/B920865H
Citation: Chem. Commun., 2010,46, 392-394
  •   Request permissions

    Directed evolution of gold nanoparticle delivery to cells

    N. Li, T. Larson, H. H. Nguyen, K. V. Sokolov and A. D. Ellington, Chem. Commun., 2010, 46, 392
    DOI: 10.1039/B920865H

    If you are not the author of this article and you wish to reproduce material from it in a third party non-RSC publication you must formally request permission using RightsLink. Go to our Instructions for using RightsLink page for details.

    Authors contributing to RSC publications (journal articles, books or book chapters) do not need to formally request permission to reproduce material contained in this article provided that the correct acknowledgement is given with the reproduced material.

    Reproduced material should be attributed as follows:

    • For reproduction of material from NJC:
      Reproduced from Ref. XX with permission from the Centre National de la Recherche Scientifique (CNRS) and The Royal Society of Chemistry.
    • For reproduction of material from PCCP:
      Reproduced from Ref. XX with permission from the PCCP Owner Societies.
    • For reproduction of material from PPS:
      Reproduced from Ref. XX with permission from the European Society for Photobiology, the European Photochemistry Association, and The Royal Society of Chemistry.
    • For reproduction of material from all other RSC journals and books:
      Reproduced from Ref. XX with permission from The Royal Society of Chemistry.

    If the material has been adapted instead of reproduced from the original RSC publication "Reproduced from" can be substituted with "Adapted from".

    In all cases the Ref. XX is the XXth reference in the list of references.

    If you are the author of this article you do not need to formally request permission to reproduce figures, diagrams etc. contained in this article in third party publications or in a thesis or dissertation provided that the correct acknowledgement is given with the reproduced material.

    Reproduced material should be attributed as follows:

    • For reproduction of material from NJC:
      [Original citation] - Reproduced by permission of The Royal Society of Chemistry (RSC) on behalf of the Centre National de la Recherche Scientifique (CNRS) and the RSC
    • For reproduction of material from PCCP:
      [Original citation] - Reproduced by permission of the PCCP Owner Societies
    • For reproduction of material from PPS:
      [Original citation] - Reproduced by permission of The Royal Society of Chemistry (RSC) on behalf of the European Society for Photobiology, the European Photochemistry Association, and RSC
    • For reproduction of material from all other RSC journals:
      [Original citation] - Reproduced by permission of The Royal Society of Chemistry

    If you are the author of this article you still need to obtain permission to reproduce the whole article in a third party publication with the exception of reproduction of the whole article in a thesis or dissertation.

    Information about reproducing material from RSC articles with different licences is available on our Permission Requests page.

Search articles by author

Spotlight

Advertisements