Jump to main content
Jump to site search

Issue 3, 2010
Previous Article Next Article

Unique metabolites of Pestalotiopsis fici suggest a biosynthetic hypothesis involving a Diels–Alder reaction and then mechanistic diversification

Author affiliations

Abstract

Chloropupukeanolides A (1) and B (2), unprecedented spiroketal peroxides, and chloropupukeanone A (3), three highly functionalized metabolites featuring a chlorinated pupukeanane core, were isolated from an endophytic fungus Pestalotiopsis fici, with 1 showing significant anti-HIV-1 and cytotoxic effects.

Graphical abstract: Unique metabolites of Pestalotiopsis fici suggest a biosynthetic hypothesis involving a Diels–Alder reaction and then mechanistic diversification

Back to tab navigation

Publication details

The article was received on 17 Sep 2009, accepted on 23 Oct 2009 and first published on 13 Nov 2009


Article type: Communication
DOI: 10.1039/B918330B
Citation: Chem. Commun., 2010,46, 460-462
  •   Request permissions

    Unique metabolites of Pestalotiopsis fici suggest a biosynthetic hypothesis involving a Diels–Alder reaction and then mechanistic diversification

    L. Liu, S. Niu, X. Lu, X. Chen, H. Zhang, L. Guo and Y. Che, Chem. Commun., 2010, 46, 460
    DOI: 10.1039/B918330B

Search articles by author

Spotlight

Advertisements