Jump to main content
Jump to site search

Issue 6, 2010
Previous Article Next Article

Selective electrochemical discrimination between dopamine and phenethylamine-derived psychotropic drugs using electrodes modified with an acyclic receptor containing two terminal 3-alkoxy-5-nitroindazole rings

Author affiliations

Abstract

Electrochemical discrimination between dopamine and psychotropic drugs which have in common a skeletal structure of phenethylamine, can be obtained using acyclic receptors L1 and L2, containing two terminal 3-alkoxy-5-nitroindazole rings. Upon attachment to graphite electrodes, L1 and L2 exhibit a well-defined, essentially reversible solid state electrochemistry in contact with aqueous media, based on electrolyte-assisted reduction processes involving successive cation and anion insertion/binding. As a result, a distinctive, essentially Nernstian electrochemical response is obtained for phenethylammonium ions of methamphetamine (METH), p-methoxyamphetamine (PMA), amphetamine (AMPH), mescaline (MES), homoveratrylamine (HOM), phenethylamine (PEA) and dopamine (DA) in aqueous media.

Graphical abstract: Selective electrochemical discrimination between dopamine and phenethylamine-derived psychotropic drugs using electrodes modified with an acyclic receptor containing two terminal 3-alkoxy-5-nitroindazole rings

Back to tab navigation

Publication details

The article was received on 11 Feb 2010, accepted on 19 Mar 2010 and first published on 21 Apr 2010


Article type: Paper
DOI: 10.1039/C0AN00082E
Citation: Analyst, 2010,135, 1449-1455
  •   Request permissions

    Selective electrochemical discrimination between dopamine and phenethylamine-derived psychotropic drugs using electrodes modified with an acyclic receptor containing two terminal 3-alkoxy-5-nitroindazole rings

    A. Doménech, P. Navarro, V. J. Arán, B. Muro, N. Montoya and E. García-España, Analyst, 2010, 135, 1449
    DOI: 10.1039/C0AN00082E

Search articles by author

Spotlight

Advertisements