Optical imaging of non-fluorescent nanoparticle probes in live cells

Gufeng Wang; Anthony S. Stender; Wei Sun; Ning Fang

doi:10.1039/B916395F

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Analyst

Issue 2, 2010

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Optical imaging of non-fluorescent nanoparticle probes in live cells

Gufeng Wang , Anthony S. Stender , Wei Sun and Ning Fang

Analyst, 2010, 135, 215-221

DOI: 10.1039/B916395F
Received 11 Sep 2009, Accepted 03 Dec 2009
First published on the web 17 Dec 2009

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Precise imaging of cellular and subcellular structures and dynamic processes in live cells is crucial for fundamental research in life sciences and in medical applications. Non-fluorescent nanoparticles are an important type of optical probe used in live-cell imaging due to their photostability, large optical cross-sections, and low toxicity. Here, we provide an overview of recent developments in the optical imaging of non-fluorescent nanoparticle probes in live cells.

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