Recent highlights in the synthesis of highly functionalized pyrimidines

Marco Radi; Silvia Schenone; Maurizio Botta

doi:10.1039/B906445A

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Organic & Biomolecular Chemistry

Issue 14, 2009

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Recent highlights in the synthesis of highly functionalized pyrimidines

Marco Radi , Silvia Schenone and Maurizio Botta

Org. Biomol. Chem., 2009, 7, 2841-2847

DOI: 10.1039/B906445A
Received 02 Apr 2009, First published on the web 12 Jun 2009

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Abstract
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The pyrimidine scaffold represents an important pharmacophore endowed with a wide range of pharmacological activities according to the specific decoration of the heterocycle. This perspective article will briefly outline the most interesting approaches recently reported for the synthesis of highly functionalized pyrimidine derivatives.

Abstract from Methods in Organic Synthesis 2009

A review, with 39 references, describing recent developments in the convergent synthesis and functionalisation of pyrimidine scaffolds.

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Organic & Biomolecular Chemistry

Recent highlights in the synthesis of highly functionalized pyrimidines

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