Total synthesis of a furostan saponin, timosaponin BII

Shuihong Cheng; Yuguo Du; Baiping Ma; Dawei Tan

doi:10.1039/B905091D

skip RSC | ChemSpider | Feedback

Home > Journals > Organic & Biomolecular ... > Total synthesis of a fu...

Authors & Referees | Librarians

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

Organic & Biomolecular Chemistry

Issue 15, 2009

More about this Journal
Editorial Board
Submit an Article

Follow Journal | |

Journal Home | RSC Journals

Paper

Previous Article | Next Article

Total synthesis of a furostan saponin, timosaponin BII

Shuihong Cheng , Yuguo Du , Baiping Ma and Dawei Tan

Org. Biomol. Chem., 2009, 7, 3112-3118

DOI: 10.1039/B905091D
Received 12 Mar 2009, Accepted 15 May 2009
First published on the web 15 Jun 2009

Please wait while Download options loads

Request Permissions

Abstract
Cited by
Related Content

The natural timosaponin BII, (25S)-26-O-β-D-glucopyranosyl-22-hydroxy-5β-furostane-3β,26-diol-3-O-β-D-glucopyranosyl-(1→2)-β-D-galactopyranoside, isolated from the rhizomes of Anemarrhena asphodeloides Bunge (Liliaceae), has been efficiently synthesized in ten steps and 18% overall yield. The strategy of using a partially protected glycosyl donor was applied to facilitate target synthesis. The cytotoxic activities of structurally related compounds were evaluated against HL-60 human promyelocytic leukaemia cells.

Abstract from Natural Product Updates 2009

No abstract available

Supplementary Info

¹H and ¹³C NMR spectra for compounds 1, 4, 7, 10, 13, 14, 15, 17, 18, 20
PDF (5660K)

Terms & Conditions|Privacy |Accessibility|ACAP Enabled

Organic & Biomolecular Chemistry

Total synthesis of a furostan saponin, timosaponin BII

Log in (Free Access)

Log in (Subscriber Access)

Supplementary Info

Articles By