Saponins as novel TNF-α inhibitors: isolation of saponins and a nor-pseudoguaianolide from Parthenium hysterophorus

Bhahwal Ali Shah; Renu Chib; Pankaj Gupta; Vijay Kumar Sethi; Surrinder Koul; Samar Singh Andotra; Amit Nargotra; Sujata Sharma; Anjali Pandey; Sarang Bani; Basant Purnima; Subhash Chandra Taneja

doi:10.1039/B902041A

skip RSC | ChemSpider | Feedback

Home > Journals > Organic & Biomolecular ... > Saponins as novel TNF-α...

Authors & Referees | Librarians

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

Organic & Biomolecular Chemistry

Issue 16, 2009

More about this Journal
Editorial Board
Submit an Article

Follow Journal | |

Journal Home | RSC Journals

Paper

Previous Article | Next Article

Saponins as novel TNF-α inhibitors: isolation of saponins and a nor-pseudoguaianolide from Parthenium hysterophorus

Bhahwal Ali Shah , Renu Chib , Pankaj Gupta , Vijay Kumar Sethi , Surrinder Koul , Samar Singh Andotra , Amit Nargotra , Sujata Sharma , Anjali Pandey , Sarang Bani , Basant Purnima and Subhash Chandra Taneja

Org. Biomol. Chem., 2009, 7, 3230-3235

DOI: 10.1039/B902041A
Received 05 Feb 2009, Accepted 13 May 2009
First published on the web 17 Jun 2009

Please wait while Download options loads

Request Permissions

Abstract
Cited by
Compounds
Related Content

Two novel saponins and a 13-nor-pseudoguaianolide designated as hysterolactone were isolated from Parthenium hysterophorus. The two saponins were found to be potent inhibitors of TNF-α. Their mode of inhibition was studied through molecular modeling. The wet lab results were in concordance with the data obtained from docking experiments.

Abstract from Natural Product Updates 2009

No abstract available

This may take some time to load.

Terms & Conditions|Privacy |Accessibility|ACAP Enabled

Organic & Biomolecular Chemistry

Saponins as novel TNF-α inhibitors: isolation of saponins and a nor-pseudoguaianolide from Parthenium hysterophorus

Log in (Free Access)

Log in (Subscriber Access)

Supplementary Info

Articles By