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Issue 5, 2009
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Palladium-catalyzed decarboxylative cross-coupling reaction of cinnamic acid with aryl iodide

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Abstract

A highly effective decarboxylative cross-coupling reaction of cinnamic acid with aryl iodide catalyzed by the combination of palladium chloride and CyJohnPhos in the presence of Ag2CO3 as an additive is described. The desired carbon-carbon bond formation proceeds efficiently with good functional-group tolerance.

Graphical abstract: Palladium-catalyzed decarboxylative cross-coupling reaction of cinnamic acid with aryl iodide

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Publication details

The article was received on 05 Dec 2008, accepted on 05 Jan 2009 and first published on 14 Jan 2009


Article type: Communication
DOI: 10.1039/B821870F
Citation: Org. Biomol. Chem., 2009,7, 863-865
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    Palladium-catalyzed decarboxylative cross-coupling reaction of cinnamic acid with aryl iodide

    Z. Wang, Q. Ding, X. He and J. Wu, Org. Biomol. Chem., 2009, 7, 863
    DOI: 10.1039/B821870F

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