Fluorescent amino acids: advances in protein-extrinsic fluorophores

Alan Roy Katritzky; Tamari Narindoshvili

doi:10.1039/B818908K

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Organic & Biomolecular Chemistry

Issue 4, 2009

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Fluorescent amino acids: advances in protein-extrinsic fluorophores

Alan Roy Katritzky and Tamari Narindoshvili

Org. Biomol. Chem., 2009, 7, 627-634

DOI: 10.1039/B818908K
Received 24 Oct 2008, First published on the web 24 Dec 2008

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Fluorescent labeling is today of paramount importance to biological studies and numerous chemical dyes are used extensively to label biological specimens. This perspective highlights interesting aspects of fluorescent labeling by fluorescent peptides and small organic fluorophores that can be incorporated into proteins by genetic fusion to produce a fluorescent label. While many fluorescence applications rely on the use of intrinsic fluorophores, the development of new extrinsic fluorophores remains an essential element for the design of new fluorescent probes.

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Organic & Biomolecular Chemistry

Fluorescent amino acids: advances in protein-extrinsic fluorophores

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