Synthesis and stereochemical determination of the spirastrellolides

Ian Paterson; Stephen M. Dalby

doi:10.1039/B906991G

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Natural Product Reports

Issue 7, 2009

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Synthesis and stereochemical determination of the spirastrellolides

Ian Paterson and Stephen M. Dalby

Nat. Prod. Rep., 2009, 26, 865-873

DOI: 10.1039/B906991G
Received 07 Apr 2009, First published on the web 29 Apr 2009

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This Highlight summarises synthetic efforts towards the marine sponge-derived antimitotic agent spirastrellolide A and its congeners, including the first total synthesis by Paterson and co-workers.

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Synthesis and stereochemical determination of the spirastrellolides

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