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Issue 8, 2009
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Mirror image phage display—a method to generate D-peptideligands for use in diagnostic or therapeutical applications

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Abstract

Mirror image phage display is a straightforward approach to identify new potentially therapeutically active D-enantiomeric peptides. Such D-peptides are more resistant to proteolytic degradation compared to L-peptides. In this review, several examples of mirror image phage display derived D-peptides with therapeutical potential are introduced and discussed.

Graphical abstract: Mirror image phage display—a method to generate d-peptideligands for use in diagnostic or therapeutical applications

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Publication details

The article was received on 27 Feb 2009, accepted on 30 Apr 2009 and first published on 12 Jun 2009


Article type: Review Article
DOI: 10.1039/B904138A
Citation: Mol. BioSyst., 2009,5, 783-786
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    Mirror image phage display—a method to generate D-peptideligands for use in diagnostic or therapeutical applications

    S. A. Funke and D. Willbold, Mol. BioSyst., 2009, 5, 783
    DOI: 10.1039/B904138A

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