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Issue 6, 2009
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Myxobacteria—‘microbial factories’ for the production of bioactive secondary metabolites

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Abstract

In this article, we briefly review the potential of myxobacteria as ‘natural product factories’ by highlighting results from the recently sequenced myxobacterial model strain Myxococcus xanthus. We will focus on the production of polyketides, non-ribosomally-made peptides, and their hybrids, and discuss the evaluation of biosynthetic potential using genome-based methods, as well as biosynthetic process engineering.

Graphical abstract: Myxobacteria—‘microbial factories’ for the production of bioactive secondary metabolites

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Publication details

The article was received on 20 Jan 2009, accepted on 24 Mar 2009 and first published on 23 Apr 2009


Article type: Review Article
DOI: 10.1039/B901287G
Citation: Mol. BioSyst., 2009,5, 567-574
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    Myxobacteria—‘microbial factories’ for the production of bioactive secondary metabolites

    S. C. Wenzel and R. Müller, Mol. BioSyst., 2009, 5, 567
    DOI: 10.1039/B901287G

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