Jump to main content
Jump to site search

Issue 6, 2009
Previous Article Next Article

Domains in bacterial membranes and the action of antimicrobial agents

Author affiliations

Abstract

A major advance in the concept of the fluid mosaic model of biological membranes in recent years has been the appreciation of the domain structure of membranes. This concept is now well developed with mammalian plasma membranes but is an emerging focus with regard to bacterial membranes. In addition to bacterial domains that form spontaneously, it is possible to induce the separation of anionic and zwitterionic lipids with certain cationic antimicrobial agents. As a consequence, the bacterial species for which these agents will be toxic can be predicted on the basis of the lipid composition of the bacterial membrane.

Graphical abstract: Domains in bacterial membranes and the action of antimicrobial agents

Back to tab navigation

Publication details

The article was received on 06 Jan 2009, accepted on 26 Feb 2009 and first published on 15 Apr 2009


Article type: Review Article
DOI: 10.1039/B900278M
Citation: Mol. BioSyst., 2009,5, 580-587
  •   Request permissions

    Domains in bacterial membranes and the action of antimicrobial agents

    R. M. Epand and R. F. Epand, Mol. BioSyst., 2009, 5, 580
    DOI: 10.1039/B900278M

Search articles by author

Spotlight

Advertisements