Automated high-throughput cell microsurgery on-chip

Kwanghun Chung; Hang Lu

doi:10.1039/B910703G

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Lab on a Chip

Issue 19, 2009

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Automated high-throughput cell microsurgery on-chip

Kwanghun Chung and Hang Lu

Lab Chip, 2009, 9, 2764-2766

DOI: 10.1039/B910703G
Received 02 Jun 2009, Accepted 11 Aug 2009
First published on the web 19 Aug 2009

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Abstract
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Compounds
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Laser cell kill is an established tool for studying cells' roles during development and behavior, but its use has been limited due to the manual and low-throughput nature. We demonstrate here a technique combining multiplexing microfluidic manipulation of Caenorhabditis elegans and software for image processing and automation, allowing for high-throughput cell ablations.

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