Rapid switching of chemical signals in microfluidic devices

Albert J. Bae; Carsten Beta; Eberhard Bodenschatz

doi:10.1039/B905521E

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Lab on a Chip

Issue 21, 2009

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Rapid switching of chemical signals in microfluidic devices

Albert J. Bae , Carsten Beta and Eberhard Bodenschatz

Lab Chip, 2009, 9, 3059-3065

DOI: 10.1039/B905521E
Received 18 Mar 2009, Accepted 15 Jun 2009
First published on the web 03 Jul 2009

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Abstract
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We present an analysis of concentration switching times in microfluidic devices. The limits of rapid switching are analyzed based on the theory of dispersion by Taylor and Aris and compared to both experiments and numerical simulations. We focus on switching times obtained by photo-activation of caged compounds in a micro-flow (flow photolysis). The performance of flow photolysis is compared to other switching techniques. A flow chart is provided to facilitate the application of our theoretical analysis to microfluidic switching devices.

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Supplementary notes on the Taylor-Aris dispersion
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