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Issue 34, 2009
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Antimicrobial activity of methylene blue and toluidine blue O covalently bound to a modified silicone polymer surface

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Abstract

Methylene Blue or Toluidine Blue O were covalently bound to an activated silicone polymer by means of an amide condensation reaction. UV-visible absorption spectra confirmed that the dye was surface bound. The new polymers with covalently attached dye display significant bactericidal activity against Escherichia coli and Staphylococcus epidermidis with a 99.999% reduction in viable bacteria after four minutes exposure to a low power laser.

Graphical abstract: Antimicrobial activity of methylene blue and toluidine blue O covalently bound to a modified silicone polymer surface

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Publication details

The article was received on 18 Mar 2009, accepted on 05 Jun 2009 and first published on 06 Jul 2009


Article type: Paper
DOI: 10.1039/B905495B
Citation: J. Mater. Chem., 2009,19, 6167-6171
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    Antimicrobial activity of methylene blue and toluidine blue O covalently bound to a modified silicone polymer surface

    C. Piccirillo, S. Perni, J. Gil-Thomas, P. Prokopovich, M. Wilson, J. Pratten and I. P. Parkin, J. Mater. Chem., 2009, 19, 6167
    DOI: 10.1039/B905495B

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