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Issue 35, 2009
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Mesostructured multifunctional nanoparticles for imaging and drug delivery

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Abstract

Mesostructured silica particles (∼100 nm diameter with ∼2 nm pores) prepared by surfactant-templated sol–gel techniques are versatile supports that can be easily derivatized with active molecules to create multifunctional materials. By deliberately placing active molecules in different regions of the mesostructure, fluorescent molecules, molecular machines, targeting ligands, and metal nanocrystals can be combined on a single particle. This review highlights the research in which multiple components are incorporated onto mesoporous silica for simultaneous imaging and delivery of molecules in biological applications.

Graphical abstract: Mesostructured multifunctional nanoparticles for imaging and drug delivery

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Publication details

The article was received on 09 Feb 2009, accepted on 07 May 2009 and first published on 19 Jun 2009


Article type: Highlight
DOI: 10.1039/B902462J
Citation: J. Mater. Chem., 2009,19, 6251-6257
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    Mesostructured multifunctional nanoparticles for imaging and drug delivery

    M. Liong, S. Angelos, E. Choi, K. Patel, J. F. Stoddart and J. I. Zink, J. Mater. Chem., 2009, 19, 6251
    DOI: 10.1039/B902462J

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