Laser ablation inductively coupled plasma mass spectrometry—current shortcomings, practical suggestions for improving performance, and experiments to guide future development

Carmen C. Garcia; Helmut Lindner; Kay Niemax

doi:10.1039/B813124B

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Journal of Analytical Atomic Spectrometry

Issue 1, 2009

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Laser ablation inductively coupled plasma mass spectrometry—current shortcomings, practical suggestions for improving performance, and experiments to guide future development

Carmen C. Garcia , Helmut Lindner and Kay Niemax

J. Anal. At. Spectrom., 2009, 24, 14-26

DOI: 10.1039/B813124B
Received 29 Jul 2008, Accepted 15 Aug 2008
First published on the web 01 Oct 2008

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Experimental parameters and processes important in laser ablation such as the wavelength, fluence and pulse width of the laser, the form of the ablation cell, the cell gas, the particle transport and atomization in the ICP have an impact on the analytical performance of laser ablation inductively coupled mass spectrometry. The paper discusses the influence of the aforementioned parameters and processes on LA-ICP-MS and presents proposals to map out strategies for optimum LA-ICP-MS analyses. Additionally, experiments are identified which still need to be done for better understanding of the relevant processes and further improvement of the analytical performance of the technique.

Abstract from Mass Spectrometry Bulletin 2009

Inductively coupled plasma/MS, Laser - other uses, Laser ablation.

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Journal of Analytical Atomic Spectrometry

Laser ablation inductively coupled plasma mass spectrometry—current shortcomings, practical suggestions for improving performance, and experiments to guide future development

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