Enantioselective aldol reaction of cyclic ketones with aryl aldehydes catalyzed by a cyclohexanediamine derived salt in the presence of water

Jin-Hong Lin; Cheng-Pan Zhang; Ji-Chang Xiao

doi:10.1039/B916583E

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Green Chemistry

Issue 11, 2009

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Enantioselective aldol reaction of cyclic ketones with aryl aldehydes catalyzed by a cyclohexanediamine derived salt in the presence of water

Jin-Hong Lin , Cheng-Pan Zhang and Ji-Chang Xiao

Green Chem., 2009, 11, 1750-1753

DOI: 10.1039/B916583E
Received 11 Aug 2009, Accepted 01 Sep 2009
First published on the web 11 Sep 2009

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Water was found to be a suitable reaction medium for the direct asymmetric aldol reaction of various cyclic ketones with aryl aldehydes catalyzed by a primary-tertiary diamine-Brønsted acid.

Abstract from Catalysts & Catalysed Reactions 2010

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Abstract from Methods in Organic Synthesis 2010

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Green Chemistry

Enantioselective aldol reaction of cyclic ketones with aryl aldehydes catalyzed by a cyclohexanediamine derived salt in the presence of water

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