An efficient aqueous microwave-assisted Suzuki–Miyaura cross-coupling reaction in the thiazole series

Anita Cohen; Maxime D. Crozet; Pascal Rathelot; Patrice Vanelle

doi:10.1039/B916123F

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Green Chemistry

Issue 11, 2009

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An efficient aqueous microwave-assisted Suzuki–Miyaura cross-coupling reaction in the thiazole series

Anita Cohen , Maxime D. Crozet , Pascal Rathelot and Patrice Vanelle

Green Chem., 2009, 11, 1736-1742

DOI: 10.1039/B916123F
Received 25 May 2009, Accepted 10 Aug 2009
First published on the web 03 Sep 2009

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A new simple, rapid and high yielding synthesis of various 5-substituted thiazoles by Suzuki–Miyaura cross-coupling reaction is described using microwave irradiation in aqueous medium without organic co-solvent in the presence of tetrabutylammonium bromide.

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An efficient aqueous microwave-assisted Suzuki–Miyaura cross-coupling reaction in the thiazole series

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