Antibiofilm activities of 1-alkyl-3-methylimidazolium chloride ionic liquids

Louise Carson; Peter K. W. Chau; Martyn J. Earle; Manuela A. Gilea; Brendan F. Gilmore; Sean P. Gorman; Maureen T. McCann; Kenneth R. Seddon

doi:10.1039/B821842K

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Green Chemistry

Issue 4, 2009

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Antibiofilm activities of 1-alkyl-3-methylimidazolium chloride ionic liquids

Louise Carson , Peter K. W. Chau , Martyn J. Earle , Manuela A. Gilea , Brendan F. Gilmore , Sean P. Gorman , Maureen T. McCann and Kenneth R. Seddon

Green Chem., 2009, 11, 492-497

DOI: 10.1039/B821842K
Received 05 Dec 2008, Accepted 22 Jan 2009
First published on the web 18 Feb 2009

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Microbial biofilms are ubiquitous in nature and represent the predominant mode of growth of microorganisms. A general characteristic of biofilm communities is that they tend to exhibit significant tolerance to antimicrobial challenge compared with planktonic bacteria of the same species The antibiofilm activity of a series of 1-alkyl-3-methylimidazolium chloride ionic liquids has been evaluated against a panel of clinically significant microbial pathogens, including MRSA. A comparison of antimicrobial activity against planktonic bacteria and established biofilms is presented. In general, these ionic liquids possess potent, broad spectrum antibiofilm activity.

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Louise Carson
Peter K. W. Chau
Martyn J. Earle
Manuela A. Gilea
Brendan F. Gilmore
Sean P. Gorman
Maureen T. McCann
Kenneth R. Seddon

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Green Chemistry

Antibiofilm activities of 1-alkyl-3-methylimidazolium chloride ionic liquids

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