Jump to main content
Jump to site search

Issue 7, 2009
Previous Article Next Article

Green chemistry aspects of fluorous techniques—opportunities and challenges for small-scale organic synthesis

Author affiliations

Abstract

Described in this paper is a personal overview of the green chemistry aspects of fluorous technologies. The unique phase separation and broad combinatorial capabilities of fluorous technologies have led to the development of fluorous chromatography-free separations, chemical recycling techniques, atom economic reactions, energy-focused microwave reactions, metal-free organocatalysis, aqueous media reactions, and modified reagents. These green chemistry techniques have been demonstrated in discovery chemistry, medicinal chemistry, and academic research labs dealing with small-scale organic synthesis. Issues such as the environmental impact of fluorous chemicals are also discussed.

Graphical abstract: Green chemistry aspects of fluorous techniques—opportunities and challenges for small-scale organic synthesis

Back to tab navigation

Publication details

The article was received on 20 Nov 2008, accepted on 27 Apr 2009 and first published on 14 May 2009


Article type: Critical Review
DOI: 10.1039/B820740B
Citation: Green Chem., 2009,11, 911-920
  •   Request permissions

    Green chemistry aspects of fluorous techniques—opportunities and challenges for small-scale organic synthesis

    W. Zhang, Green Chem., 2009, 11, 911
    DOI: 10.1039/B820740B

Search articles by author

Spotlight

Advertisements