A novel physiologic sampling pump capable of rapid response to breathing

Larry Lee; Michael Flemmer; Eun Gyung Lee; Martin Harper; Ming-I Lin; William Groves; Andris Freivalds; James Slaven

doi:10.1039/B816699D

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Journal of Environmental Monitoring

Issue 5, 2009

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A novel physiologic sampling pump capable of rapid response to breathing

Larry Lee , Michael Flemmer , Eun Gyung Lee , Martin Harper , Ming-I Lin , William Groves , Andris Freivalds and James Slaven

J. Environ. Monit., 2009, 11, 1020-1027

DOI: 10.1039/B816699D
Received 24 Sep 2008, Accepted 18 Feb 2009
First published on the web 03 Mar 2009

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Abstract
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The merits of using physiologic sampling pumps (PSPs) instead of using constant-flow sampling pumps, i.e., “traditional sampling pumps” (TSPs), are discussed. A novel PSP that overcomes shortcomings of previous PSP designs is presented. Calibrated valves are used to obviate pump inertia that has limited the system response and accuracy of prior work. Technologies that provide minute ventilation (_E) of subjects in real time may therefore be used to the limit of their own accuracies to sample inhalation exposures. Analysis of the design and data from a prototype are presented to show how air sampling can be modulated to follow breathing.

Abstract from Chemical Hazards in Industry 2009

The merits of using physiologic sampling pumps (PSPs) instead of using constant-flow sampling pumpsi.e.“traditional sampling pumps” (TSPs), are discussed. A novel PSP that overcomes shortcomings of previous PSP designs is presented. Calibrated valves are used to obviate pump inertia that has limited the system response and accuracy of prior work. Technologies that provide minute ventilation (V_E) of subjects in real time may therefore be used to the limit of their own accuracies to sample inhalation exposures. Analysis of the design and data from a prototype are presented to show how air sampling can be modulated to follow breathing.

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Articles By

Larry Lee
Michael Flemmer
Eun Gyung Lee
Martin Harper
Ming-I Lin
William Groves
Andris Freivalds
James Slaven

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Journal of Environmental Monitoring

A novel physiologic sampling pump capable of rapid response to breathing

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