Structural features of the Zn2+ complex with the single repeat region of “prion related protein” (PrP-rel-2) of zebrafish zPrP63–70 fragment

Francesca Camponeschi; Elena Gaggelli; Henryk Kozłowski; Daniela Valensin; Gianni Valensin

doi:10.1039/B907626N

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

Structural features of the Zn²⁺ complex with the single repeat region of “prion related protein” (PrP-rel-2) of zebrafish zPrP63–70 fragment†

Francesca Camponeschi,^a Elena Gaggelli,^a Henryk Kozłowski,*^b Daniela Valensin^a and Gianni Valensin*^a

Author affiliations

* Corresponding authors

^a Department of Chemistry, University of Siena, via Aldo Moro, Siena, Italy
E-mail: valensin@unisi.it

^b Faculty of Chemistry, University of Wrocław, F. Joliot-Curie 14, Wroclaw, Poland
E-mail: henrykoz@wchuwr.chem.uni.wroc.pl

Abstract

The interaction between Zn²⁺ and the single repeat of PrP-rel-2 of zebrafish at physiological pH was investigated by NMR spectroscopy; the chemical shift mapping and the proton–proton distances were used to obtain the structural model of the Zn²⁺ complex.

Download options Please wait...

Supplementary files

Peptide synthesis, NMR measurements, ¹H–¹³C HSQC spectra of the apo and metal boundzPrP63–70 PDF (353K)

Article information

DOI: https://doi.org/10.1039/B907626N
Article type: Communication
Submitted: 17 Feb 2009
Accepted: 21 Apr 2009
First published: 30 Apr 2009

Download Citation

Dalton Trans., 2009, 4643-4645

Permissions

Request permissions

Structural features of the Zn²⁺ complex with the single repeat region of “prion related protein” (PrP-rel-2) of zebrafish zPrP63–70 fragment

F. Camponeschi, E. Gaggelli, H. Kozłowski, D. Valensin and G. Valensin, Dalton Trans., 2009, 4643 DOI: 10.1039/B907626N

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

Dalton Transactions