Jump to main content
Jump to site search

Issue 5, 2009
Previous Article Next Article

Transition metal catalysed reactions of alcohols using borrowing hydrogen methodology

Author affiliations

Abstract

The reactivity of alcohols can be enhanced by the temporary removal of hydrogen using a transition metal catalyst to generate an intermediate aldehyde or ketone. The so-formed carbonyl compound has a greater reactivity towards nucleophilic addition accommodating the in situ formation of imines or alkenes. The return of hydrogen from the catalyst leads to the formation of new C–N and C–C bonds, often with water as the only reaction by-product.

Graphical abstract: Transition metal catalysed reactions of alcohols using borrowing hydrogen methodology

Back to tab navigation

Publication details

The article was received on 01 Aug 2008, accepted on 23 Sep 2008 and first published on 21 Nov 2008


Article type: Perspective
DOI: 10.1039/B813383B
Citation: Dalton Trans., 2009,0, 753-762
  •   Request permissions

    Transition metal catalysed reactions of alcohols using borrowing hydrogen methodology

    T. D. Nixon, M. K. Whittlesey and J. M. J. Williams, Dalton Trans., 2009, 0, 753
    DOI: 10.1039/B813383B

Search articles by author

Spotlight

Advertisements