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Issue 45, 2009
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Enhanced resistance of DNAnanostructures to enzymatic digestion

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Abstract

The ability of nucleases to perform their catalytic functions depends on the sequence and structural features of target DNA substrates. Due to their size and shape, several DNA tetrahedra are resistant to the action of specific and non-specific nucleases. Such enhanced stability is a key requirement for DNAnanostructures to be useful as delivery vehicles.

Graphical abstract: Enhanced resistance of DNAnanostructures to enzymatic digestion

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Publication details

The article was received on 27 Aug 2009, accepted on 23 Sep 2009 and first published on 13 Oct 2009


Article type: Communication
DOI: 10.1039/B917661F
Citation: Chem. Commun., 2009,0, 7036-7038
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    Enhanced resistance of DNAnanostructures to enzymatic digestion

    J. Keum and H. Bermudez, Chem. Commun., 2009, 0, 7036
    DOI: 10.1039/B917661F

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