Specific recognition of lectins by oligonucleotide glycoconjugates and sorting on a DNA microarray

Jing Zhang; Gwladys Pourceau; Albert Meyer; Sébastien Vidal; Jean-Pierre Praly; Eliane Souteyrand; Jean-Jacques Vasseur; François Morvan; Yann Chevolot

doi:10.1039/B915132J

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Chemical Communications

Issue 44, 2009

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Specific recognition of lectins by oligonucleotide glycoconjugates and sorting on a DNA microarray

Jing Zhang , Gwladys Pourceau , Albert Meyer , Sébastien Vidal , Jean-Pierre Praly , Eliane Souteyrand , Jean-Jacques Vasseur , François Morvan and Yann Chevolot

Chem. Commun., 2009, 6795-6797

DOI: 10.1039/B915132J
Received 24 Jul 2009, Accepted 17 Sep 2009
First published on the web 30 Sep 2009

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Abstract
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Two glycoconjugates bearing different DNA tags are mixed in solution with lectins; both interact with their specific lectin and the resulting complexes are sorted, according to their DNA sequences, at the surface of micro-reactors bearing the immobilised complementary DNA sequences.

Supplementary Info

Experimental details of the synthesis of glycomimetics IIincluding HPLC and MS data. Experimental details related toglycoarray fabrication and protocols
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Articles By

Jing Zhang
Gwladys Pourceau
Albert Meyer
Sébastien Vidal
Jean-Pierre Praly
Eliane Souteyrand
Jean-Jacques Vasseur
François Morvan
Yann Chevolot

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Chemical Communications

Specific recognition of lectins by oligonucleotide glycoconjugates and sorting on a DNA microarray

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