Palladium-catalysed arylative cyclisation of N-allylacetamides with aryl halides yielding benzyl-substituted oxazolines

Daishi Fujino; Sayuri Hayashi; Hideki Yorimitsu; Koichiro Oshima

doi:10.1039/B912895F

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Chemical Communications

Issue 38, 2009

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Palladium-catalysed arylative cyclisation of N-allylacetamides with aryl halides yielding benzyl-substituted oxazolines

Daishi Fujino , Sayuri Hayashi , Hideki Yorimitsu and Koichiro Oshima

Chem. Commun., 2009, 5754-5756

DOI: 10.1039/B912895F
Received 30 Jun 2009, Accepted 21 Aug 2009
First published on the web 03 Sep 2009
This article is part of the collection: Selective Catalysis for Organic Synthesis

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Treatment of N-allylacetamide with aryl halide in the presence of sodium t-butoxide and a palladium catalyst leads to arylative cyclisation to provide the corresponding benzyl-substituted oxazoline in high yield.

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Chemical Communications

Palladium-catalysed arylative cyclisation of N-allylacetamides with aryl halides yielding benzyl-substituted oxazolines

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