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Efficient synthesis of dendrimersvia a thiol–yne and esterification process and their potential application in the delivery of platinum anti-cancer drugs
Centre for Advanced Macromolecular Design (CAMD), School of Chemical Science and Engineering, The University of New South Wales, Sydney, Australia
E-mail: M.Stenzel@unsw.edu.au
; Tel: +61-293854344
Chem. Commun., 2009, 6291-6293
DOI:
10.1039/B910340F
Received
27 May 2009,
Accepted
21 Aug 2009
First published online
04 Sep 2009
A combination of thiol–yne chemistry and esterification reactions were successfully applied for the preparation of dendrimers with an array of terminal functionalities via the divergent growth strategy; maximizing the number of reactive chain ends whilst minimizing the number of reaction steps required in the process.
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