One-pot cascade Michael–Michael–Aldol condensation for diastereoselective synthesis of nitro-substituted cyclohexanes

Yunfeng Chen; Cheng Zhong; Xiaohua Sun; Novruz G. Akhmedov; Jeffrey L. Petersen; Xiaodong Shi

doi:10.1039/B909766J

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Chemical Communications

Issue 34, 2009

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One-pot cascade Michael–Michael–Aldol condensation for diastereoselective synthesis of nitro-substituted cyclohexanes

Yunfeng Chen , Cheng Zhong , Xiaohua Sun , Novruz G. Akhmedov , Jeffrey L. Petersen and Xiaodong Shi

Chem. Commun., 2009, 5150-5152

DOI: 10.1039/B909766J
Received 18 May 2009, Accepted 06 Jul 2009
First published on the web 31 Jul 2009

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Abstract
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A one-pot reaction of nitroalkenes and enones was developed for the preparation of nitro-vinyl-substituted cyclohexanes, which could be simply converted into poly-N-heterocycles.

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Supplementary Info

Experimental details, X-ray measurement, and ¹H NMR and ¹³C NMR for all compounds
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Crystal structure data
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Articles By

Yunfeng Chen
Cheng Zhong
Xiaohua Sun
Novruz G. Akhmedov
Jeffrey L. Petersen
Xiaodong Shi

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Chemical Communications

One-pot cascade Michael–Michael–Aldol condensation for diastereoselective synthesis of nitro-substituted cyclohexanes

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