Issue 30, 2009
From the journal:

Chemical Communications

Catalytic amide formation with α′-hydroxyenones as acylating reagents†‡

Pei-Chen Chiang,a   Yoonjoo Kima  and  Jeffrey W. Bode*a  

* Corresponding authors

a Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, USA
E-mail: bode@sas.upenn.edu
Tel: +1 215 573 1953

Abstract

α′-Hydroxyenones undergo clean, catalytic amidations with amines promoted by the combination of an N-heterocyclic carbene and 1,2,4-triazole.

Graphical abstract: Catalytic amide formation with α′-hydroxyenones as acylating reagents

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Article information

DOI
https://doi.org/10.1039/B909360E
Article type
Communication
Submitted
14 May 2009
Accepted
17 Jun 2009
First published
06 Jul 2009

Chem. Commun., 2009, 4566-4568

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Catalytic amide formation with α′-hydroxyenones as acylating reagents

P. Chiang, Y. Kim and J. W. Bode, Chem. Commun., 2009, 4566 DOI: 10.1039/B909360E

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