A DNA-binding Gd chelate for the detection of cell death by MRI

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Chemical Communications

Issue 29, 2009

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Elisabeth Garanger , Scott A. Hilderbrand , Joseph T. Blois , David E. Sosnovik , Ralph Weissleder and Lee Josephson

Chem. Commun., 2009, 4444-4446

DOI: 10.1039/B907375B
Received 14 Apr 2009, Accepted 18 May 2009
First published on the web 12 Jun 2009

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GadoTO, a MR contrast agent for the detection of cell death, consists of a nucleic acid-binding fluorophore attached to a gadolinium chelate.

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