Issue 24, 2009
From the journal:

Chemical Communications

G-quadruplex-based DNAzyme for sensitive mercury detection with the naked eye†

Tao Li,ab   Bingling Li,ab   Erkang Wang*ab  and  Shaojun Dong*ab  

* Corresponding authors

a State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin, China
E-mail: dongsj@ciac.jl.cn, ekwang@ciac.jl.cn
Fax: (+86) 431-85689711
Tel: (+86) 431-85262101

b Graduate School of the Chinese Academy of Sciences, Beijing, China

Abstract

Hg2+ is able to inhibit the peroxidase-like DNAzyme function of a T-containing G-quadruplex DNAviaHg2+-mediated T–T base pairs, which enables the visual detection of Hg2+ in the TMB–H2O2 reaction system with high selectivity and sensitivity.

Graphical abstract: G-quadruplex-based DNAzyme for sensitive mercury detection with the naked eye

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Article information

DOI
https://doi.org/10.1039/B903993G
Article type
Communication
Submitted
25 Feb 2009
Accepted
16 Apr 2009
First published
07 May 2009

Chem. Commun., 2009, 3551-3553

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G-quadruplex-based DNAzyme for sensitive mercury detection with the naked eye

T. Li, B. Li, E. Wang and S. Dong, Chem. Commun., 2009, 3551 DOI: 10.1039/B903993G

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