New method to prepare very stable and biocompatible fluorescent silica nanoparticles

Shin-Woo Ha; Corinne E. Camalier; George R. Beck Jr.; Jin-Kyu Lee

doi:10.1039/B902195G

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Chemical Communications

Issue 20, 2009

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New method to prepare very stable and biocompatible fluorescent silica nanoparticles

Shin-Woo Ha , Corinne E. Camalier , George R. Beck Jr. and Jin-Kyu Lee

Chem. Commun., 2009, 2881-2883

DOI: 10.1039/B902195G
Received 02 Feb 2009, Accepted 13 Mar 2009
First published on the web 06 Apr 2009

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A new synthetic method has been developed to prepare fluorescent silica nanoparticles without employing isothiocyanated dye molecules and (3-aminopropyl)triethoxysilane (APS) for the thiourea linkage formation; the resulting fluorescent silica nanoparticles show excellent photochemical, thermal and pH stabilities and a good biocompatibility with over 85% viability from various cell types.

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Chemical Communications

New method to prepare very stable and biocompatible fluorescent silica nanoparticles

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