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Issue 21, 2009
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Electrochemical assay of superoxide based on biomimetic enzyme at highly conductive TiO2 nanoneedles: from principle to applications in living cells

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Abstract

A novel strategy for extremely durable, reliable, and selective in situ real-time determination of superoxide anion (O2˙) based on direct electron transfer of a biomimeticsuperoxide dismutase (SOD), Mn3(PO4)2, at highly conductive TiO2 nanoneedles is reported for the first time, and is further exploited for the determination of O2˙ from living normal and cancer ovary cells directly adhered onto the modified surface, suggesting that O2˙ might be proposed as a biomarker of cancer.

Graphical abstract: Electrochemical assay of superoxide based on biomimetic enzyme at highly conductive TiO2 nanoneedles: from principle to applications in living cells

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Publication details

The article was received on 02 Feb 2009, accepted on 16 Mar 2009, published on 07 Apr 2009 and first published online on 07 Apr 2009


Article type: Communication
DOI: 10.1039/B902150G
Citation: Chem. Commun., 2009, 3014-3016
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    Electrochemical assay of superoxide based on biomimetic enzyme at highly conductive TiO2 nanoneedles: from principle to applications in living cells

    Y. Luo, Y. Tian and Q. Rui, Chem. Commun., 2009, 3014
    DOI: 10.1039/B902150G

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