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Issue 19, 2009
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Chemo-/regioselective synthesis of 6-unsubstituted dihydropyrimidinones, 1,3-thiazines and chromonesvia novel variants of Biginelli reaction

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Abstract

A novel and facile cascade Biginelli-like assembly employing enaminone, aldehyde and urea/thiourea has been developed, which provides a highly chemo- and regioselective synthesis of new dihydropyrimidinones, 1,3-thiazines and chromones by altering particular functional groups in the reactants.

Graphical abstract: Chemo-/regioselective synthesis of 6-unsubstituted dihydropyrimidinones, 1,3-thiazines and chromonesvia novel variants of Biginelli reaction

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Publication details

The article was received on 19 Jan 2009, accepted on 10 Mar 2009 and first published on 30 Mar 2009


Article type: Communication
DOI: 10.1039/B901112A
Citation: Chem. Commun., 2009, 2768-2770
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    Chemo-/regioselective synthesis of 6-unsubstituted dihydropyrimidinones, 1,3-thiazines and chromonesvia novel variants of Biginelli reaction

    J. Wan and Y. Pan, Chem. Commun., 2009, 2768
    DOI: 10.1039/B901112A

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