This website uses cookies to give you the best user experience. If you continue
without changing your settings we'll assume you are happy to receive all RSC cookies.
You can change your cookie settings by navigating to our Privacy and Cookies page and following the instructions. These instructions
are also obtainable from the privacy link at the bottom of any RSC page.
Department of Chemistry & Chemical Biology, University of New Mexico, Albuquerque, USA
E-mail: wwang@unm.edu
; Fax: (+1) 505 277 2609
; Tel: (+1) 505 277 0756
Chem. Commun., 2009, 2136-2138
DOI:
10.1039/B900777F
Received
14 Jan 2009,
Accepted
23 Feb 2009
First published online
12 Mar 2009
Organocatalytic enantioselective conjugate addition of α-fluoroketoesters to nitroolefins efficiently catalyzed by a cinchona alkaloid-derivative affords versatile non-enolizable ketoesters by forming two consecutive fluorinated quaternary and tertiary chiral carbon centers with excellent enantioselectivity.