Issue 13, 2009
From the journal:

Chemical Communications

Oxovanadium(iv)-based near-IR PDT agents: design to biological evaluation†‡

Pijus K. Sasmal,a   Sounik Saha,a   Ritankar Majumdar,b   Rajan R. Digheb  and  Akhil R. Chakravarty*a  

* Corresponding authors

a Department of Inorganic and Physical Chemistry, Indian Institute of Science, Bangalore, India
E-mail: arc@ipc.iisc.ernet.in
Fax: +91-80-23600683
Tel: +91-80-22932533

b Department of Molecular Reproduction, Development and Genetics, Indian Institute of Science, Bangalore, India

Abstract

An oxovanadium(IV) complex of dipyridophenazine, as a potent metal-based PDT agent, shows efficient DNA photocleavage activity at near-IR region and high photocytotoxicity in both UV-A and visible light in HeLa cells.

Graphical abstract: Oxovanadium(iv)-based near-IR PDT agents: design to biological evaluation

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Article information

DOI
https://doi.org/10.1039/B822229K
Article type
Communication
Submitted
10 Dec 2008
Accepted
23 Jan 2009
First published
16 Feb 2009

Chem. Commun., 2009, 1703-1705

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Oxovanadium(IV)-based near-IR PDT agents: design to biological evaluation

P. K. Sasmal, S. Saha, R. Majumdar, R. R. Dighe and A. R. Chakravarty, Chem. Commun., 2009, 1703 DOI: 10.1039/B822229K

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