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Reversible molecular switching of molecular beacon: controlling DNA hybridization kinetics and thermodynamics using mercury(II) ions

Ronghua Yang,*ab   Jianyu Jin,b   Liping Long,ac   Yongxiang Wang,b   Hao Wangb and   Weihong Tan*ad  
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Corresponding authors
a
State Key Lab of Chemo/Biosensing and Chemometrics, Biomedical Engineering Center, College of Chemistry and Chemical Engineering, Hunan University, Changsa, China
E-mail: Yangrh@pku.edu.cn;
Fax: +86 10-62751708
b
College of Chemistry and Molecular Engineering, Peking University, Beijing, China
c
Department of Chemistry and Environment Engineering, Hunan City University, Hunan, China
d
dCenter for Research at the Bio/Nano Interface, Department of Chemistry and Department of Physiology and Functional Genomics, Shands Cancer Center and UF Genetics Institute, University of Florida, Gainesville, USA
E-mail: tan@chem.ufl.edu
Chem. Commun., 2009, 322-324

DOI: 10.1039/B816638B
Received 23 Sep 2008, Accepted 30 Oct 2008
First published online 20 Nov 2008
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