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Issue 4, 2009
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3-Mercaptopropionic acid-mediated synthesis of peptide and protein thioesters

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Abstract

Peptides and proteins fragment sequence-specifically in the presence of 3-mercaptopropionic acid to afford thioesters which can be used in native chemical ligation reactions.

Graphical abstract: 3-Mercaptopropionic acid-mediated synthesis of peptide and protein thioesters

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Publication details

The article was received on 10 Sep 2008, accepted on 10 Oct 2008 and first published on 05 Nov 2008


Article type: Communication
DOI: 10.1039/B815888F
Citation: Chem. Commun., 2009,0, 407-409
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    3-Mercaptopropionic acid-mediated synthesis of peptide and protein thioesters

    J. Kang, J. P. Richardson and D. Macmillan, Chem. Commun., 2009, 0, 407
    DOI: 10.1039/B815888F

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