Investigations of optical activity of natural products and chiral pharmaceuticals using liquid crystal technologies

Peter Raynes; Stephen J. Cowling; John W. Goodby

doi:10.1039/B9AY00126C

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Analytical Methods

Issue 2, 2009

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Investigations of optical activity of natural products and chiral pharmaceuticals using liquid crystal technologies

Peter Raynes , Stephen J. Cowling and John W. Goodby

Anal. Methods, 2009, 1, 88-92

DOI: 10.1039/B9AY00126C
Received 28 Jul 2009, Accepted 24 Aug 2009
First published on the web 30 Sep 2009

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In this article we demonstrate the use of liquid crystal technologies in the determination of enantiomeric excess and in the sensing of molecular chirality, particularly at values near to zero. We use this technique to investigate the optical purities of the commercially available chiral natural product, menthol, and in the investigation of the optical activity of racemic ibuprofen.

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Analytical Methods

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