Vibrational spectroscopy: a clinical tool for cancer diagnostics

Catherine Kendall; Martin Isabelle; Florian Bazant-Hegemark; Joanne Hutchings; Linda Orr; Jaspreet Babrah; Rebecca Baker; Nicholas Stone

doi:10.1039/B822130H

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Analyst

Issue 6, 2009

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Vibrational spectroscopy: a clinical tool for cancer diagnostics

Catherine Kendall , Martin Isabelle , Florian Bazant-Hegemark , Joanne Hutchings , Linda Orr , Jaspreet Babrah , Rebecca Baker and Nicholas Stone

Analyst, 2009, 134, 1029-1045

DOI: 10.1039/B822130H
First published on the web 23 Mar 2009
This article is part of the collection: Optical Diagnosis

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Vibrational spectroscopy techniques have demonstrated potential to provide non-destructive, rapid, clinically relevant diagnostic information. Early detection is the most important factor in the prevention of cancer. Raman and infrared spectroscopy enable the biochemical signatures from biological tissues to be extracted and analysed. In conjunction with advanced chemometrics such measurements can contribute to the diagnostic assessment of biological material. This paper also illustrates the complementary advantage of using Raman and FTIR spectroscopy technologies together. Clinical requirements are increasingly met by technological developments which show promise to become a clinical reality. This review summarises recent advances in vibrational spectroscopy and their impact on the diagnosis of cancer.

Abstract from Analytical Abstracts 2010

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Articles By

Catherine Kendall
Martin Isabelle
Florian Bazant-Hegemark
Joanne Hutchings
Linda Orr
Jaspreet Babrah
Rebecca Baker
Nicholas Stone

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