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Issue 6, 2009
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Vibrational spectroscopy: a clinical tool for cancer diagnostics

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Abstract

Vibrational spectroscopy techniques have demonstrated potential to provide non-destructive, rapid, clinically relevant diagnostic information. Early detection is the most important factor in the prevention of cancer. Raman and infrared spectroscopy enable the biochemical signatures from biological tissues to be extracted and analysed. In conjunction with advanced chemometrics such measurements can contribute to the diagnostic assessment of biological material. This paper also illustrates the complementary advantage of using Raman and FTIR spectroscopy technologies together. Clinical requirements are increasingly met by technological developments which show promise to become a clinical reality. This review summarises recent advances in vibrational spectroscopy and their impact on the diagnosis of cancer.

Graphical abstract: Vibrational spectroscopy: a clinical tool for cancer diagnostics

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Publication details

The article was first published on 23 Mar 2009


Article type: Critical Review
DOI: 10.1039/B822130H
Citation: Analyst, 2009,134, 1029-1045
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    Vibrational spectroscopy: a clinical tool for cancer diagnostics

    C. Kendall, M. Isabelle, F. Bazant-Hegemark, J. Hutchings, L. Orr, J. Babrah, R. Baker and N. Stone, Analyst, 2009, 134, 1029
    DOI: 10.1039/B822130H

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