Amphiphilic nanoassemblies for the detection of peptides and proteins using fluorescence and mass spectrometry

Malar A. Azagarsamy; Andrea Gomez-Escudero; Volkan Yesilyurt; Richard W. Vachet; S. Thayumanavan

doi:10.1039/B818484D

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Analyst

Issue 4, 2009

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Amphiphilic nanoassemblies for the detection of peptides and proteins using fluorescence and mass spectrometry

Malar A. Azagarsamy , Andrea Gomez-Escudero , Volkan Yesilyurt , Richard W. Vachet and S. Thayumanavan

Analyst, 2009, 134, 635-649

DOI: 10.1039/B818484D
First published on the web 10 Mar 2009
This article is part of the collection: Materials for Detection

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Abstract
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Compounds
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Amphiphilic nanostructures provide unique environments for molecules that are incompatible with the solvent to be sequestered within their interior. These internal environments provide opportunities for concentrating an analyte or transducer molecule for detection, and the functional groups within the amphiphiles provide an opportunity for incorporating specificity or selectivity toward analytes. In this review, we discuss ways in which amphiphilic assemblies can be used to detect peptides and proteins with a particular emphasis on facially amphiphilic polymers and dendrimers.

Abstract from Mass Spectrometry Bulletin 2009

Peptides, Sample handling, Proteins.

Abstract from Analytical Abstracts 2009

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Malar A. Azagarsamy
Andrea Gomez-Escudero
Volkan Yesilyurt
Richard W. Vachet
S. Thayumanavan

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Amphiphilic nanoassemblies for the detection of peptides and proteins using fluorescence and mass spectrometry

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