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Issue 6, 2008
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Direct visualization of phase transition dynamics in binary supported phospholipid bilayers using imaging ellipsometry

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Abstract

Via imaging ellipsometry, we study the phase transition dynamics induced by selective gelation of one component in a binary supported phopholipid bilayer. We find the modulation of two attendant morphological features: emergence of extended defect chains due to a net change in the molecular areas and fractal-like domains suggesting weak line tension. A time-lapse analysis of the ellipsometric images reveals the cluster size of 4–20 molecules undergoing gelation indicating weak cooperativity. These results demonstrate the use of ellipsometry for in situ, label-free, non-contact, and large-area imaging of dynamics in interfacial films.

Graphical abstract: Direct visualization of phase transition dynamics in binary supported phospholipid bilayers using imaging ellipsometry

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Publication details

The article was received on 28 Jan 2008, accepted on 14 Apr 2008 and first published on 28 Apr 2008


Article type: Communication
DOI: 10.1039/B801390J
Citation: Soft Matter, 2008,4, 1161-1164
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    Direct visualization of phase transition dynamics in binary supported phospholipid bilayers using imaging ellipsometry

    A. W. Szmodis, C. D. Blanchette, A. A. Levchenko, A. Navrotsky, M. L. Longo, C. A. Orme and A. N. Parikh, Soft Matter, 2008, 4, 1161
    DOI: 10.1039/B801390J

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