Nanomechanics of polymer gels and biological tissues: A critical review of analytical approaches in the Hertzian regime and beyond

David C. Lin; Ferenc Horkay

doi:10.1039/B714637J

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Soft Matter

Issue 4, 2008

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Nanomechanics of polymer gels and biological tissues: A critical review of analytical approaches in the Hertzian regime and beyond

David C. Lin and Ferenc Horkay

Soft Matter, 2008, 4, 669-682

DOI: 10.1039/B714637J
Received 21 Sep 2007, Accepted 17 Dec 2007
First published on the web 05 Feb 2008

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We survey recent progress in the application of nanoindentation to characterize the local mechanical properties of polymer gels and biological tissues. We review the theories, analytical models based thereon, and data processing techniques commonly used to determine elastic properties of these classes of materials by instrumented nanoindentation. Examples from the testing of synthetic and biological gels are used to illustrate the limitations of existing theories and approaches. Emphasis is placed on the need for contact mechanics models that more accurately represent the large-strain behaviour of soft matter.

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Soft Matter

Nanomechanics of polymer gels and biological tissues: A critical review of analytical approaches in the Hertzian regime and beyond

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